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Hypotonic Riboflavin Collagen Cross Linking for Thinner Corneas

Hypotonic Riboflavin Collagen Cross Linking for Thinner Corneas


By Rajesh Khanna, MD

Collagen cross linking has recently been invented in this century. A lot of people who would benefit greatly from this novel treatment have missed the recommended inclusion criteria. This has been because either their cornea has thinned out too much, developed scars or become very steep. keratoconus doctors strive to gel these patients living with keratoconus.

Researchers like Peter Hersh MD have led the way to help keratoconus sufferers. For thinner corneas a novel approach has been designed. Hyoptonic Riboflavin is with less salt and no dextran. This leads to swelling of the cornea. Normal concentration riboflavin on the other hands leads to corneal thinning. The thickness of the cornea is important to proven the uv radiation reaching the inner cells of the cornea.

Inclusion Criteria:

  • 18 years of age or older
  • A diagnosis of progressive keratoconus or a diagnosis of corneal bulging following Lasik eye surgery or PRK
  • Vision with contact lenses or glasses is worse than 20/20
  • Corneal thickness greater than 300 microns at the thinnest point

Exclusion Criteria:

  • Cornea pachymetry >400 microns
  • Corneal pachymetry ≤ 300 microns at the thinnest point .
  • Previous ocular condition (other than refractive error) in the eye(s) to be treated that may predispose the eye for future complications
  • Clinically significant corneal scarring in the CXL treatment zone
  • Pregnancy (including plan to become pregnant) or lactation during the course of the study
  • Patients with nystagmus or any other condition that would prevent a steady gaze during the CXL treatment or other diagnostic tests.
  • Patients with a current condition that, in the investigator’s opinion, would interfere with or prolong epithelial healing.

Depending on the situation patients younger than 18 can be treated. Utilizing general anesthesia even uncooperative kids, people with nystagmus can benefit from this sight saving cure.

Hope this information on Hypotonic Riboflavin Collagen Cross Linking for Thinner Corneas is helpful in the fight against Keratoconus.

Learn about Causes of Keratoconus

About the Author Rajesh Khanna, MD

Los Angeles Lasik Surgeon Rajesh Khanna MD is a recognized pioneer in Presbyopic Implants for correction of aging eyes. He has popularized Cornea Cross Linking and Intacs forKeratoconus. He is an Expert Cataract, Pterygium Eye Surgeon, A Cornea Specialist he performs Laser Corneal Transplants, DMEK, DSEK and DALK. Rajesh Khanna MD is a well known medical writer. He has published the bestseller "The miracle of Pi in Eye".He is also a columnist for the newspaper Acorn. Dr.Khanna also hosts "Medical Magic". In his spare time he hikes with his family and German Shepard or does yoga. He also plays field hockey and loves swimming.

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